Mr Jahangir Ahmed

Professional Biography

Additional Information

COVID-19 Specific Projects / Groups

I was part of the Barts tracheostomy multidisciplinary team, coordinating and providing surgical tracheostomy for the large cohort of ventilated COVID-19 patients in Barts Health to help respiratory wean.

I continue to provide a surgical head and neck cancer service during the COVID-19 era, co-ordinated via the UCLH cancer surgical hub.

Career Highlights

My highlights include:

• Graduating with an MA in experimental psychology from the University of Cambridge
• Obtaining a PhD in molecular oncology from the Barts Cancer Institute for optimising Vaccinia virus for the purposes of immunotherapy
• My consultant position in head and neck surgery, ENT at Barts Health and UCLH NHS trusts
• Establishing the transoral robotics programme at Barts Health – collaborating with the Barts respiratory team in managing patients with obstructive sleep apnoea refractory to continuous positive airway pressure therapy.

Awards

My awards include:

• The Wellcome Trust – Clinical Research Fellowship, 2012
• Barts and the London Charity Clinical Research Fellowship, 2011
• RCSEng Academic Research Fellowship, 2011
• HCW Vines Prize for pathology, Imperial College, 2000
• Steadman Prize for pathology: Gold, Imperial College, 1999
• Harmer Prize for Medicine, Kings College, Cambridge University, 1996

Memberships

I am a member of ENT-UK and the British Laryngological Association.

Cutting Edge Technologies

I have performed transoral robotic surgery and transoral CO2 laser microsurgery.

Publications

My publications include:

• A new oncolytic Vaccinia virus augments antitumor immune responses to prevent tumor recurrence and metastasis after surgery. J Immunother Cancer. 2020 Mar;8(1).
• Transient Inhibition of PI3Kδ Enhances the Therapeutic Effect of Intravenous Delivery of Oncolytic Vaccinia Virus. Mol Ther. 2020 Feb 28.
• Custom designing laryngoplasty implant using actual size CT scan images on a mobile device. Clin Otolaryngol. 2019 Jan.
• No evidence of cholesteatoma in untreated otitis media with effusion in children with primary ciliary dyskinesia. Int J Pediatr Otorhinolaryngol. 2018 Feb.
• Aberrant facial flushing following monobloc fronto-facial distraction. J Craniomaxillofac Surg. 2015 Oct.
• A marker-free system for highly efficient construction of vaccinia virus vectors using CRISPR Cas9. Mol Ther Methods Clin Dev. 2015 Sep 16;2.
• Efficiently editing the Vaccinia virus genome using the CRISPR Cas9 system. J Virol. 2015 Mar 4.
• A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer. Clin Cancer Res. 2015 Jan 15;21(2).
• MRI brain abnormalities in cochlear implant candidates: How common and how important are they? Int J Pediatr Otorhinolaryngol. 2012 Apr 10.
• Functional endoscopic balloon dilation of sinus ostia for chronic rhinosinusitis. Cochrane Database Syst Rev. July 2011.
• The extended Sistrunk procedure for the management of thyroglossal duct cysts in children: how we do it. Clin Otolaryngol. 2011 Jun;36(3).
• Impact of long-term nasopharyngeal airway on health-related quality of life of children with obstructive sleep apnea caused by syndromic craniosynostosis. J Craniofac Surg. 2011 Jan;22(1).
• Hearing and ossicular chain preservation in cholesteatoma surgery. J Laryngol Otol. 2011 Feb;125(2).
• Endaural meatoplasty: the Whipps Cross technique. J Laryngol Otol. 2011 Jan;125(1).
• Assessment of the chin in patients undergoing rhinoplasty: what proportion may benefit from chin augmentation? Otolaryngol Head Neck Surg. 2010 Feb;142(2).
• The role of the nasopharyngeal airway for OSA in syndromic craniosynostosis. Journal of Craniofacial Surgery. 19(3):659-663, May 2008.
• Treatment of pyriform fossa sinuses with monopolar diathermy. J Laryngol Otol. 2008 Aug.
• An approach to the management of paroxysmal laryngospasm. Analysis of case series and establishment of a management protocol. J Laryngol Otol. 2008 Jan 122(1).

Chapters I’ve contributed include:

• Chapter entitled ‘Laryngeal Chondrosarcoma’Ahmed, C Al-Yaghchi for ‘Laryngology: a case-based approach’, Eds J Allen, R Nouraei, G Sandhu. Plural publishing. In press.
• Chapter entitled ‘Management of the Airway in Thyroid Disorders’ Ahmed, A Mace for ‘Laryngology: a case-based approach’ Eds J Allen, R Nouraei, G Sandhu. Plural publishing. In press.
• Chapter entitled ‘Diagnosis of allergic fungal rhinosinusitis’ J Ahmed, H saleh; for ‘Landmark Papers in Otolaryngology.’ Oxford University Press.
• Chapter entitled ‘Sublingual or subcutaneous immunotherapy for allergic rhinitis?’. J Ahmed, H saleh; for ‘Landmark Papers in Otolaryngology’. Oxford University Press.
• Chapter entitled ‘Radiological imaging for non-traumatic paediatric ENT conditions’, J Ahmed, C Offiah, Y Bajaj; for ‘Head and Neck Imaging: A Multi-Disciplinary Team Approach’ Springer publishing. In press.
• Online version of Chapter 21: Special Senses: Disorders of the Ear Nose and Throat; Kumar and Clark’s Clinical Medicine 9th edition. J Ahmed, K Ghufoor.
• Chapter entitled ‘Penetrating neck trauma’ for ‘Key clinical topics in Otolaryngology’ edited by Y Bajaj et. al, commissioned by J P Medical Ltd. In Press.
• 3 book chapters for ‘Pocket Tutor ENT’. Eds Bhattacharyya and Patel. J P Medical Ltd. Dec 2011.
• Chapter entitled ‘Pre malignant lesions of the larynx, Ahmed, Ghufoor’ for Volume 4 (Laryngology, ed. A K Bhattacharyya) of Otolaryngology – Head and Neck Surgery, eds. M. V. Kirtane and C DeSouza. Theime Scientific and Medical Publishers. Dec 2013.
• Chapter entitled ‘The Lister Strain Vaccinia Virus as an anticancer Immunotherapeutic’, J Ahmed, M Yuan, G Alusi, N Lemoine, Y Wang for Gene Therapy of Cancer,3rd edition: Translational Approaches from Preclinical Studies to Clinical Implementation. Eds E C Lattime, S L Gerson. Academic Press Inc. Oct 2013.